Ms4a2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comMs4a2 ELISA Kit for Rat(Rattus norvegicus)

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Ms4a2 (Gene name),

High affinity immunoglobulin epsilon receptor subunit beta (Protein name ), FCERB_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ms4a2(Fce1b;Fcer1b);

Protein name:

High affinity immunoglobulin epsilon receptor subunit beta(FcERI);

Alternative:

IgE Fc receptor subunit beta;Fc epsilon receptor I beta-chain;Membrane-spanning 4-domains subfamily A member 2;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Tetramer of an alpha chain, a beta chain, and two disulfide linked gamma chains. Binds LILRB1. Interacts with FES/FPS (By similarity). Interacts with FGR.

Function:

High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy.

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

243

Sequence:

50:

100:

150:

200:

243:

YRIGQEFERS | KVPDDRLYEE | LHVYSPIYSA | LEDTREASAP | VVS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P13386

KEGG:

rno:25316

UniGene:

Rn.10922

Pfam:

PF04103

STRING:

10116.ENSRNOP00000028491

Uniprot:

P13386

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ELISA Kit for Rat FcERI

Cat.:

E1891r

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Rat FcERI

Cat.:

E1891m

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MSDS:

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Packing:

96T

ELISA Kit for Rat FcERI

Cat.:

E1891h

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MSDS:

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Packing:

96T

CLIA Kit for Rat FcERI

Cat.:

U1891m

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MSDS:

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Packing:

96T

CLIA Kit for Rat FcERI

Cat.:

U1891h

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MSDS:

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Packing:

96T

CLIA Kit for Rat FcERI

Cat.:

U1891r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat FcERI

Cat.:

P1891Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat FcERI

Cat.:

P1891Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat FcERI

Cat.:

P1891Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat FcERI

Protein for Rat FcERI

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Isolation and characterization of cDNAs coding for the beta subunit of the high-affinity receptor for immunoglobulin E."
Kinet J.-P. , Blank U. , Ra C. , White K. , Metzger H. , Kochan J.
Proc. Natl. Acad. Sci. U.S.A.85:6483-6487(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 11-29; 37-43 AND 217-243
2.

"The Src family kinase Fgr is critical for activation of mast cells and IgE-mediated anaphylaxis in mice."
Lee J.H. , Kim J.W. , Kim do K. , Kim H.S. , Park H.J. , Park D.K. , Kim A.R. , Kim B. , Beaven M.A. , Park K.L. , Kim Y.M. , Choi W.S.
J. Immunol.187:1807-1815(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FGR;SUBCELLULAR LOCATION

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